Blar i forfatter "Sun, Yi-Qian"

Viser treff 1-7 av 7

    • Adiposity and asthma in adults: a bidirectional Mendelian randomization analysis of the HUNT Study 

      Sun, Yi-Qian; Brumpton, Ben Michael; Langhammer, Arnulf; Chen, Yue; Kvaløy, Kirsti; Mai, Xiao-Mei (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-14)
      <i>Background</i> - We aimed to investigate the potential causal associations of adiposity with asthma overall, asthma by atopic status or by levels of symptom control in a large adult population and stratified by sex. We also investigated the potential for reverse causation between asthma and risk of adiposity.<p> <p><i>Methods</i> - We performed a bidirectional one-sample Mendelian randomisation ...

    • Assessing the role of genome-wide DNA methylation between smoking and risk of lung cancer using repeated measurements: the HUNT Study 

      Sun, Yi-Qian; Richmond, Rebecca C.; Suderman, Matthew; Min, Josine L; Battram, Thomas; Flatberg, Arnar; Beisvag, Vidar; Nøst, Therese Haugdahl; Guida, Florence; Jiang, Lin; Wahl, Sissel Gyrid Freim; Langhammer, Arnulf; Skorpen, Frank; Walker, Rosie M; Bretherick, Andrew D; Zeng, Yanni; Chen, Yue; Johansson, Mattias; Sandanger, Torkjel M; Relton, Caroline L; Mai, Xiao-Mei (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-17)
      <i>Background</i> - It is unclear if smoking-related DNA methylation represents a causal pathway between smoking and risk of lung cancer. We sought to identify novel smoking-related DNA methylation sites in blood, with repeated measurements, and to appraise the putative role of DNA methylation in the pathway between smoking and lung cancer development.<br><br> <i>Methods</i> - We derived a nested ...

    • Friedman Score in Relation to Compliance and Treatment Response in Nonsevere Obstructive Sleep Apnea 

      Berg, Lars Martin; Ankjell, Torun Karina Solheim; Sun, Yi-Qian; Trovik, Tordis A; Sjögren, Anders; Rikardsen, Oddveig G; Moen, Ketil; Hellem, Sølve; Bugten, Vegard (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-19)
      Nonsevere obstructive sleep apnea (OSA) is most often treated with a continuous positive airway pressure (CPAP) device or a mandibular advancement splint (MAS). However, patient compliance with these treatments is difficult to predict. Improvement in apnea-hypopnea index (AHI) is also somewhat unpredictable in MAS treatment. In this study, we investigated the association between Friedman tongue ...

    • Health-related quality of life and sleep quality after 12 months of treatment in non-severe obstructive sleep apnea: A randomized clinical trial with Continuous Positive Airway Pressure and Mandibular Advancement Splints 

      Berg, Lars Martin; Ankjell, Torun Karina Solheim; Sun, Yi-Qian; Trovik, Tordis A; Rikardsen, Oddveig G; Sjögren, Anders; Moen, Ketil; Hellem, Sølve; Bugten, Vegard (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-01)
      In this randomized controlled trial, patients with non-severe obstructive sleep apnea (OSA) were treated with continuous positive airway pressure (CPAP) or a twin block mandibular advancement splint (MAS). The primary objective was to compare how CPAP and MAS treatments change the health-related quality of life (HRQoL) and self-reported sleep quality of patients after 12 months of treatment. In ...

    • Increased expression of individual genes in whole blood is associated with late-stage lung cancer at and close to diagnosis 

      Urbarova, Ilona Halva; Skogholt, Anne Heidi; Sun, Yi-Qian; Mai, Xiao-Mei; Grønberg, Bjørn Henning; Sandanger, Torkjel Manning; Sætrom, Pål; Nøst, Therese Haugdahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-25)
      Lung cancer (LC) mortality rates are still increasing globally. As survival is linked to stage, there is a need to identify markers for earlier LC diagnosis and individualized treatment. The whole blood transcriptome of LC patients represents a source of potential LC biomarkers. We compared expression of > 60,000 genes in whole blood specimens taken from LC cases at diagnosis (n = 128) and controls ...

    • Prevalence of malnutrition among older adults in a population-based study - The HUNT Study 

      Kolberg, Marit; Paur, Ingvild; Sun, Yi-Qian; Gjøra, Linda; Skjellegrind, Håvard Kjesbu; Thingstad, Anne Pernille Mæhle; Strand, Bjørn Heine; Selbæk, Geir; Natland Fagerhaug, Tone; Thoresen, Lene (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-19)
      Background Malnutrition is common in older adults and is associated with increased morbidity and mortality rates. Aim The aim of the study is to describe the prevalence of malnutrition based on low BMI, involuntary weight loss, and reduced food intake, in a Norwegian population of community-dwelling older adults and older adults living in nursing homes. Methods This population-based study ...

    • Self-reported sleep quality with mandibular advancement device or continuous positive airway pressure: A randomized clinical trial on patients with mild and moderate obstructive sleep apnea 

      Berg, Lars Martin; Ankjell, Torun Karina Solheim; Trovik, Tordis A; Sjögren, Anders; Rikardsen, Oddveig G; Moen, Ketil; Sun, Yi-Qian; Bugten, Vegard (Journal article; Tidsskriftartikkel, 2020)
      <i>Study</i> - objectives To compare self-reported sleep quality, treatment compliance and respiratory event index (REI) after 4 months of treatment with mandibular advancement device (MAD) or continuous positive airway pressure (CPAP) in mild and moderate obstructive sleep apnea (OSA). <p> <p><i>Methods</i> - 104 patients with mild or moderate OSA were randomly allocated to MAD or CPAP treatment, ...